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Nausea, diarrhoea and weight loss were the most common adverse events recorded in patients in the four trials, but they were generally mild to moderate in intensity and generally occurred in the first weeks of treatment.
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Professor Leonardo Fabbri, Professor of Respiratory Medicine, University of Modena and Reggio Emilia, Italy, and lead author of the six-month studies, said: Roflumilast has a novel mode of action and has the potential to become the first of a new class ofGeneric Aldactone Buying Protonix Legally - Southampton
A significant worsening of symptoms called an exacerbation or lung attack can last several weeks.
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